NK154183A and B, antitumor substances produced by Streptomyces sp.

نویسندگان

  • K Tsuchiya
  • C Kimura
  • K Nishikawa
  • T Harada
  • T Nishikiori
  • K Tatsuta
چکیده

aApplied Microbiology Research Center, Nippon Kayaku Co., Ltd., 225-1, Koshikiya, Horigome, Ageo-shi, Saitama 362, Japan bResearch and Development Division, Pharmaceutical Group, Nippon Kayaku Co., Ltd., 3-31-12 Shimo, Kita-ku, Tokyo 115, Japan cGraduate School of Science and Engineering, Advanced Research Institute for Science and Engineering, Waseda University, Ohkubo, Shinjuku, Tokyo 169, Japan

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Study of Anti-fungal Effects of Isolated streptomyces sp. from Gorgan Areas

Abstract Bachground and objectives:Streptomyces is the most important genus in Actinomycetes family.The Streptomycetes are widely used in industry producing numerous chemical compounds including antibiotics, enzymes and anti- tumor agents. The aim of this study was to isolate soil-borne Streptomyces producing antimicrobial substances from soil of Golestan province of Iran and to survey anti-fun...

متن کامل

Cytotoxicity effect of secondary metabolites of Streptomyces koyangensis and Streptomyces tunisiensis isolated from saline soils of Garmsar City on human breast cancer cell line (MCF-7, IBRC C10082)

Background: Streptomyces is one of the most important prokaryotic microorganisms, and their secondary metabolites have high antimicrobial and cytotoxic properties. Three-quarters of the antibiotics known to be produced by these bacteria. As a result, finding new effective compounds from these microorganisms can be a way to treat cancer. The aim of this study was to isolate and screen halophilic...

متن کامل

Pyrronamycin A and B, novel antitumor antibiotics containing pyrrole-amide repeating unit, produced by Streptomyces sp.

topoisomerases, we have screened cultures of actinomycetes and fungi for their ability to inhibit selectively the growth of bacteriophage TP-68 at the concentration that shows no apparent antibacterial activity against NUB3620. In the course of microbial screening, strain KYI1768 was identified to produce active metabolites. We described here production including fermentation and isolation, and...

متن کامل

SW-163C and E, novel antitumor depsipeptides produced by Streptomyces sp. II. Structure elucidation.

SW-163C and E are novel antitumor antibiotics, which belong to quinomycin family, isolated from the culture broth of Streptomyces sp. SNA15896. These compounds were determined to be cyclic depsipeptides having 3-hydroxyquinaldic acid as a chromophore and a sulfur-containing intramolecular cross linkage through various spectroscopic analyses.

متن کامل

A new antitumor substance, BE-18591, produced by a streptomycete. II. Structure determination.

In the course of screening for new antitumor substances, BE-18591 (la) was isolated from cultures of Streptomyces sp. BA18591X). The isolation and physico-chemical properties together with biological activities are reported in the preceding paper. In this paper, the structure elucidation is described. The physico-chemical properties of la were summarized in a previous paper1*. The molecular for...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Journal of antibiotics

دوره 49 12  شماره 

صفحات  -

تاریخ انتشار 1996